Infection generates natural immunity… And it’s good, long lasting and cheap!

COVID infection generates natural immunity, which seems good and long lasting and cheap, lots of evidence below.

Here a video and some scientific studies proving it:

Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study; https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(21)00575-4.pdf

Biological studies

Dan et al (2021) Science; Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection; https://www.science.org/doi/full/10.1126/science.abf4063

95% of participants tested retained immune memory at about 6 months after having COVID-19 More than 90% of participants had CD4+ T-cell memory at 1 month, and 6–8 months after having COVID-19

Wang et al (2021), Science; Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants; https://www.science.org/doi/full/10.1126/science.abh1766

Previous SARS-CoV-2 infection, with an ancestral variant produce antibodies that cross-neutralise emerging variants of concern with high potency Epidemiological studies

Hansen et al (2021), Lancet; Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study; https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(21)00575-4.pdf

People who had had COVID-19 previously were around 80·5% protected against reinfection

Pilz et al (2021), European Journal of Clinical Investigation; SARS-CoV-2 re-infection risk in Austria; https://onlinelibrary.wiley.com/doi/full/10.1111/eci.13520

Sheehan et al (2021) Clinical Infectious Diseases; Reinfection rates among patients who previously tested positive for COVID-19: a retrospective cohort study; https://academic.oup.com/cid/article/73/10/1882/6170939

Shrestha et al (2021), preprint; Necessity of COVID-19 vaccination in previously infected individuals; https://www.medrxiv.org/content/10.1101/2021.06.01.21258176v3

Retrospective cohort study in the USA, People who had had COVID-19 previously were 100% protected against reinfection

Gazit et al (2021), Preprint; Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections; https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1

Kojima et al (2021), reprint; Incidence of severe acute respiratory syndrome coronavirus-2 infection among previously infected or vaccinated employees; https://www.medrxiv.org/content/10.1101/2021.07.03.21259976v2

Laboratory staff routinely screened for SARS-CoV-2, people who had had COVID-19 previously were 100% protected against reinfection

Clinical studies

Hall et al (2021), Lancet; SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England:
a large, multicentre, prospective cohort study (SIREN); https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(21)00675-9.pdf

Large, multicentre, prospective cohort study Previous COVID-19 diagnosis, 84% decreased risk of infection

Letizia et al (2021), Lancet; Respiratory Medicine, SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study; https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600(21)00158-2.pdf

Prospective cohort of US Marines, seropositive young adults were 82% protected against reinfection

Adnan et al (2021), Clinical Infectious Diseases; Reinfection With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Patients Undergoing Serial Laboratory Testing; https://academic.oup.com/cid/article/74/2/294/6251701

N = 9,119, serial tests Reinfection rates, 0.7% So Risk of repeat SARS-CoV-2 infection decreased by 80·5–100% among those who had had COVID-19 Protection from reinfection is strong and persists for more than 10 months of follow-up

Turner, et al (2021), Nature; SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans; https://www.nature.com/articles/s41586-021-03647-4

Madhuumita et al (2021), Plos One; T cell response to SARS-CoV-2 infection in humans: A systematic review; https://journals.plos.org/plosone/articled=10.1371%2Fjournal.pone.0245532

SARS-CoV-2 infection induces specific and durable T-cell immunity

Nina et al (2020), Nature; SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls; https://www.nature.com/articles/s41586-020-2550-z

Memory B-cell response to SARS-CoV-2 evolves between 1·3 and 6·2 months after infection, which is consistent with longer-term protection Some people who have recovered from COVID-19 might not benefit from COVID-19 vaccination

Raw et al (2021), Journal of Infection; Previous COVID-19 infection, but not Long-COVID, is associated with increased adverse events following BNT162b2/Pfizer vaccination; https://www.journalofinfection.com/article/S0163-4453(21)00277-2/fulltext

Study found that previous COVID-19 was associated with increased adverse events following vaccination with Pfizer

Meanwhile, in Switzerland, proof of recovered infection, in the past 12 months are considered equally protected as fully vaccinated… https://www.schengenvisainfo.com/news/switzerland-plans-to-extend-covid-certificate-requirement-until-mid-november/

Even if you haven’t read all these scientific publications, now you know that infection generates natural immunity… And it’s good, long lasting and cheap!

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